So to the question does Zoloft cause insomnia? The answer is without a doubt a yes! Most patients who were being treated for OCD seemed to experience cases of insomnia, while women with PMDD did not. We strongly suggest and encourage you to consult with a licensed physician for answers to any questions you may have about these or other medications. Serotonin impacts every part of your body, from your emotions to your motor skills. Serotonin is considered a natural mood stabilizer. It’s the chemical that helps with sleeping, eating, and. 150 mg by itself is not too much, depending on your size and weight, but it sounds like you have a paradoxical effect.more anxiety rather than less, and this sometimes happens for people because Zoloft has a stimulating effect. Depression medications (antidepressant drugs) are the most commonly prescribed drug class for treating depression. Depression is a serious condition that often can be effectively treated with available therapies. Liver blood tests are some of the most commonly performed blood tests. These tests can be used to assess liver functions or liver injury. An initial step in detecting liver damage is a simple blood test to determine the level of certain liver enzymes (proteins) in the blood. Zoloft is the brand name of sertraline, an antidepressant used to treat major depressive disorders. Zoloft is in a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). A recent study published in the New England Journal of Medicine found Zoloft and cognitive behavioral therapy to be highly effective in the treatment of reasonably severe anxiety disorders in. Brain Stimulation May Soothe Severe Depression. THURSDAY, March 28, 2019 – For those who suffer debilitating depression, stimulating the brain can bring desperately needed relief, new research shows. User Reviews for Zoloft to treat Depression. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.